SCHEMBL15712533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15712529	0.91	KCNQ3 (0.54)	KCNQ3KCNQ2KCNQ4KCNQ5ERBB2
	SCHEMBL15712210	0.87	ERBB2 (0.48)	ERBB2EGFRERBB4NR1I2P2RX7
	SCHEMBL15712122	0.87	ERBB2 (0.48)	KCNQ3KCNQ2KCNQ4KCNQ5ERBB2
	SCHEMBL15712361	0.86	ERBB2 (0.47)	ERBB2EGFRERBB4NR1I2HDAC8
	SCHEMBL15712561	0.85	ERBB2 (0.51)	KCNQ3KCNQ2KCNQ4KCNQ5ERBB2
	SCHEMBL15712256	0.84	ERBB2 (0.46)	ERBB2EGFRERBB4NR1I2P2RX7
	SCHEMBL15712370	0.83	ERBB2 (0.47)	ERBB2EGFRERBB4NR1I2HDAC8
	SCHEMBL18746342	0.83	KCNQ3 (0.48)	KCNQ3KCNQ2KCNQ4KCNQ5ERBB2
	SCHEMBL15712831	0.81	SYK (0.48)	ERBB2EGFRERBB4NR1I2HDAC8
	SCHEMBL15712897	0.81	CNR1 (0.42)	KCNQ3KCNQ2KCNQ4KCNQ5ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.