SCHEMBL15712968 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	AR	P10275	8/20	0.40

▸	PGR	P06401	3/20	0.39

▸	CXCR1	P25024	1/20	0.35

▸	CXCR2	P25025	1/20	0.35

▸	L3MBTL1	Q9Y468	1/20	0.35

▸	MMP1	P03956	2/20	0.33

▸	MMP2	P08253	2/20	0.33

▸	MMP3	P08254	2/20	0.33

▸	MMP7	P09237	2/20	0.33

▸	MMP9	P14780	2/20	0.33

▸	MMP13	P45452	2/20	0.33

▸	NR3C1	P04150	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15712958	0.88	CXCR1 (0.36)	ARPGRCXCR1CXCR2L3MBTL1
SCHEMBL1364415	0.88	AR (0.40)	ARPGRCXCR1CXCR2L3MBTL1
SCHEMBL15712940	0.86	AR (0.39)	ARPGRCXCR1CXCR2L3MBTL1
SCHEMBL12342663	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL1291460	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL12342293	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL12140365	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL1362970	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL1364405	0.86	AR (0.51)	ARPGRNR3C1
SCHEMBL1363381	0.82	AR (0.37)	ARPGRCXCR1CXCR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2260028-B1	SELECTIVE ANDROGEN RECEPTOR MODULATORS	RADIUS HEALTH INC (US)	2014-05-07	—	—	EP	disclosed