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Sugi Predict / Compounds / SCHEMBL15713151

SCHEMBL15713151

SCHEMBL15713151

Cc1ccc(-c2nnc([C@H](Nc3ccc(C#N)c(Cl)c3C)[C@@H](C)O[Si](C)(C)C(C)(C)C)o2)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.64
▸ AR P10275 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1363087 0.94 AR (0.74) PGRAR
SCHEMBL3431521 0.94 AR (0.74) PGRAR
SCHEMBL3211575 0.93 PGR (0.65) PGRAR
SCHEMBL1363919 0.93 PGR (0.62) PGRAR
SCHEMBL1363454 0.93 PGR (0.62) PGRAR
SCHEMBL12339406 0.93 PGR (0.62) PGRAR
SCHEMBL1364459 0.93 PGR (0.62) PGRAR
SCHEMBL27169489 0.93 PGR (0.62) PGRAR
SCHEMBL1364705 0.92 PGR (0.61) PGRAR
SCHEMBL1364469 0.92 PGR (0.61) PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2260028-B1 SELECTIVE ANDROGEN RECEPTOR MODULATORS RADIUS HEALTH INC (US) 2014-05-07 — — EP disclosed