Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | HTR2B | P41595 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694538 | 0.83 | KMO (0.51) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL905933 | 0.83 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL10199642 | 0.83 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| Fumaric Acid SCHEMBL8006854 | 0.74 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| Fumaric Acid SCHEMBL8009273 | 0.74 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| Fumaric Acid SCHEMBL8009278 | 0.74 | HTR2A (0.58) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| Ammonia Solution, Strong SCHEMBL905935 | 0.74 | HTR2A (0.44) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL24908252 | 0.72 | NOTUM (0.43) | HTR2AHTR2CHTR2BKMO | |
| SCHEMBL8013345 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL906040 | 0.69 | HTR2A (0.60) | HTR2AHTR2CHTR2BHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2727585-A1 | In-vivo screening method | Takeda Pharmaceutical Company Limited (JP) | 2014-05-07 | — | — | EP | disclosed |