Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 4/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.49 |
| ▸ | DNA2 | P51530 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714778 | 0.86 | MYC (0.50) | TSHRMAPTTDP1KDM4EL3MBTL1 | |
| SCHEMBL26752226 | 0.79 | TSHR (0.48) | TSHRMAPTTDP1KDM4EL3MBTL1 | |
| SCHEMBL33663 | 0.77 | TSHR (1.00) | TSHRTDP1L3MBTL1LMNAMEN1 | |
| Phthalic Acid SCHEMBL8740470 | 0.76 | TSHR (0.83) | TSHRMAPTTDP1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6407719 | 0.76 | TSHR (0.96) | TSHRTDP1L3MBTL1LMNAMEN1 | |
| Ammonia Solution, Strong SCHEMBL8032064 | 0.76 | TSHR (0.96) | TSHRTDP1L3MBTL1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL5787034 | 0.76 | TSHR (0.96) | TSHRTDP1L3MBTL1LMNAMEN1 | |
| SCHEMBL6006263 | 0.75 | TSHR (0.56) | TSHRMAPTTDP1KDM4EL3MBTL1 | |
| SCHEMBL16719533 | 0.74 | MYC (0.64) | MAPTTDP1KDM4EL3MBTL1MYC | |
| SCHEMBL17769843 | 0.73 | TSHR (0.51) | TSHRMAPTTDP1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014071247-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-05-08 | — | — | WO | disclosed |