Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DNA2 | P51530 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222827 | 0.80 | TSHR (0.50) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL3729139 | 0.78 | TSHR (0.46) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL317655 | 0.75 | ALB (0.49) | ALDH1A1GAAKMT2AHPGD | |
| SCHEMBL17769843 | 0.75 | TSHR (0.51) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL15714747 | 0.75 | TSHR (0.62) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL16653775 | 0.74 | KDM4E (0.57) | TSHRL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL33663 | 0.73 | TSHR (1.00) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28969704 | 0.72 | CA12 (0.35) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL29471725 | 0.72 | TSHR (0.68) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL8610738 | 0.72 | TSHR (0.68) | TSHRDNA2CASP6CTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667728-A1 | INTRAVASCULAR DELIVERY OF NON-VIRAL NUCLEIC ACID | Mirus Bio Corporation (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005009476-A1 | INTRAVASCULAR DELIVERY OF NON-VIRAL NUCLEIC ACID | MIRUS CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |