Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468793 | 0.91 | NOTUM (0.74) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL1714277 | 0.80 | NOTUM (1.00) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL23524488 | 0.78 | NOTUM (0.53) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL23292726 | 0.78 | NOTUM (0.53) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL23524479 | 0.78 | NOTUM (0.53) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL23559490 | 0.75 | NOTUM (0.47) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL15997850 | 0.73 | NOTUM (0.84) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL23559411 | 0.71 | NOTUM (0.42) | NOTUMNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL14886588 | 0.71 | NOTUM (0.79) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL15714773 | 0.70 | POLB (0.45) | NOTUMALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014071247-A1 | PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-05-08 | — | — | WO | disclosed |