Phenylglycine

Phenylglycine

SCHEMBL157180

NC(C(=O)O)c1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.56
SRC P12931 1/20 0.56
LMNA P02545 2/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
DRD3 P35462 1/20 0.52
GRM4 Q14833 1/20 0.52
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylglycine SCHEMBL71958 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL31402004 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL27801493 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL30559595 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL11576917 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL159420 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL6718142 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL15709241 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL2003211 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL540378 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4681 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
EP-4633804-A1 PROCESS FOR PREPARING ALPHA,BETA-UNSATURATED CARBONYL COMPOUND Firmenich SA (CH) 2025-10-22 EP claimed
EP-4633805-A1 PROCESS FOR PREPARING ALLYLIC ALCOHOL Firmenich SA (CH) 2025-10-22 EP claimed
US-20250268982-A1 COMPOSITIONS AND METHODS FOR TREATMENT AND/OR PROPHYLAXIS OF PROTEINOPATHIES REGAIN THERAPEUTICS SWEDEN AB (SE) 2025-08-28 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
CN-118126023-B Pyrazole amide compound as well as preparation method and application thereof 安徽中医药大学 2025-04-11 CN claimed
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON 2025-04-03 US claimed
WO-2025042853-A1 COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND/OR TREATMENT OF ALPHA SYNUCLEIN PROTEINOPENIA IN PARKINSON'S AND OTHER DISEASES LVIS-Regain LP (US) 2025-02-27 WO claimed
WO-2025038979-A1 COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND/OR TREATMENT OF AMYLOID B PEPTIDE PROTEINOPENIA IN ALZHEIMER'S AND OTHER DISEASES LVIS-Regain LP (US) 2025-02-20 WO claimed
US-4246429-A HERBICIDES, ALGICIDES, PLANT GROWTH REGULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 1981-01-20 US claimed
EP-0003786-B1 STEREOSELECTIVE SEPARATION OF PHENYLGLYCINE DERIVATIVES AND 4-HYDROXYPHENYLGLYCINE DERIVATIVES WITH ENZYME-CONTAINING POLYMERS BAYER AG (DE) 1980-12-10 EP claimed
US-4233456-A Process for the manufacture of optically active, optionally substituted 2-amino-2-phenylacetic acid RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1980-11-11 US claimed
US-4215223-A Process for the preparation of D(-)αphenylglycine DERIVADOS DEL ETILO, S.A. 1980-07-29 US claimed
EP-0006713-A1 Novel alpha-amino-phenylacetic acid derivatives, processes for their preparation, their use as herbicidal, algicidal and plant growth regulating agents, and herbicidal, algicidal and plant growth regulating compositions containing them JANSSEN PHARMACEUTICA N.V. (BE) 1980-01-09 EP claimed
EP-0001060-A1 Process for preparing optically active unsubstituted or substituted 2-amino-2-phenyl-acetic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1979-03-21 EP claimed
US-4115439-A Process for the preparation of optically active α-phenylglycine and intermediates thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1978-09-19 US claimed
US-4007168-A Process for preparing penicillins derivatives PALOMO COLL A L 1977-02-08 US claimed
US-4005088-A Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates ANDENO B.V. (NL) 1977-01-25 US claimed
US-3933902-A Method for the optical resolution of DL-αphenylglycine ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US claimed