Phenylglycine

Phenylglycine

SCHEMBL71958

N[C@H](C(=O)O)c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.56
SRC P12931 1/20 0.56
LMNA P02545 2/20 0.54
MAPK1 P28482 1/20 0.54
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
DRD3 P35462 1/20 0.52
GRM4 Q14833 1/20 0.52
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylglycine SCHEMBL157180 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL31402004 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL27801493 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL30559595 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL11576917 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL159420 1.00 CYP2D6 (0.56) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL6718142 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL15709241 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL2003211 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10
Phenylglycine SCHEMBL540378 0.97 CYP2D6 (0.54) CYP2D6SRCLMNAMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7105 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070295-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 CN claimed
CN-122070296-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 CN claimed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 US claimed
EP-4713340-A2 COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 Calico Life Sciences LLC (US) 2026-03-25 EP claimed
US-20260062447-A1 COMPOUNDS UNIV SOUTHAMPTON (GB) 2026-03-05 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
US-20260034169-A1 STABILISED SILICIC ACID SOLUTIONS BARLAA B.V. (NL) 2026-02-05 US claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
EP-0002297-B1 PROCESS FOR THE PREPARATION OF DL-PHENYL-GLYCINE AMIDE STAMICARBON B.V. (NL) 1981-02-11 EP claimed
US-4215223-A Process for the preparation of D(-)αphenylglycine DERIVADOS DEL ETILO, S.A. 1980-07-29 US claimed
US-4172846-A Process for separating a mixture of an optically active phenylglycine amide and an optically active phenylglycine STAMICARBON, B.V. (NL) 1979-10-30 US claimed
EP-0002297-A2 Process for the preparation of DL-phenyl-glycine amide STAMICARBON B.V. (NL) 1979-06-13 EP claimed
US-4115439-A Process for the preparation of optically active α-phenylglycine and intermediates thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1978-09-19 US claimed
US-4080259-A CULTIVATION OF PSEUDOMONAS NOVO INDUSTRI A/S (DK) 1978-03-21 US claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US claimed
US-3960944-A 8-Carboxamide dibenzobicyclo(3.2.1)octadienes RIKER LABORATORIES, INC. (US) 1976-06-01 US claimed
US-3954975-A Salts of ACTH-peptides and processes for their manufacture CIBA-GEIGY CORPORATION (US) 1976-05-04 US claimed
US-3933902-A Method for the optical resolution of DL-αphenylglycine ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US claimed