SCHEMBL157188

SCHEMBL157188

NC(=O)Nc1ccccc1F

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.72
NPC1 O15118 8/20 0.72
SMN1; SMN2 Q16637 5/20 0.72
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
HTT P42858 3/20 0.58
ALDH1A1 P00352 3/20 0.56
POLB P06746 1/20 0.56
GAA P10253 2/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
PDK1 Q15118 1/20 0.53
PDK2 Q15119 1/20 0.53
PDK3 Q15120 1/20 0.53
PDK4 Q16654 1/20 0.53
EGFR P00533 1/20 0.53
MMP1 P03956 1/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757931 1.00 RAB9A (0.72) RAB9ANPC1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL8393338 0.98 RAB9A (0.69) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL4347560 0.86 RAB9A (0.71) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL6185781 0.85 RAB9A (0.53) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL3928666 0.85 GAA (0.67) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL29179553 0.85 RAB9A (0.64) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL29840068 0.85 GAA (0.67) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL30851501 0.84 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL6850971 0.84 RAB9A (0.75) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL11202950 0.84 RAB9A (1.00) RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES MONDEGO BIO, LDA. (PT) 2024-08-08 US claimed
CN-118159593-A Process for the preparation of superabsorbent polymers 株式会社LG化学 2024-06-07 CN claimed
CN-113372611-B Super-absorbent polymer capable of improving absorption speed and preparation method and application thereof 万华化学集团股份有限公司 2023-12-29 CN claimed
CN-115368290-A Plant growth regulator and preparation method thereof 湖南工业大学 2022-11-22 CN claimed
CN-113233498-B Method for adjusting perovskite luminescence wavelength by fluoride 南京邮电大学 2022-04-01 CN claimed
CN-113233498-A Method for adjusting perovskite luminescence wavelength by fluoride 南京邮电大学 2021-08-10 CN claimed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
CN-106459264-B Method for preparing super absorbent polymer and super absorbent polymer prepared thereby 株式会社LG化学 2019-10-25 CN claimed
CN-106459461-B Super absorbent polymer for absorbing blood or highly viscous liquid and method for preparing the same 株式会社LG化学 2019-09-27 CN claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
EP-1716155-A1 SUBSTITUTED THIENO¬2,3-D|PYRIMIDINES AS INHIBITORS OF TIE2 AstraZeneca AB (SE) 2006-11-02 EP claimed
CN-1247051-C Organic electroluminescent device and producing method thereof UNIV TSINGHUA (CN) 2006-03-22 CN claimed
WO-2005105757-A1 TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2005-11-10 WO claimed
WO-2005090319-A1 PROCESS FOR PREPARING BENZODIAZEPINES ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO claimed
WO-2005075483-A1 SUBSTITUTED THIENO - AND THIAZOLO - [2, 3-D] PYRIDINES AS INHIBITORS OF TIE2 ASTRAZENECA AB (SE) 2005-08-18 WO claimed
CN-1192015-C Cell adhesion inhibitors BIOGEN INC (US) 2005-03-09 CN claimed
CN-1436028-A Organic electroluminescent device and producing method thereof UNIV TSINGHUA (CN) 2003-08-13 CN claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 RAB9A 1813/4885NPC1 1857/4885SMN1; SMN2 2129/4885
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES PPM1A, TH, PPM1G RAB9A 2110/4885NPC1 2925/4885SMN1; SMN2 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.