Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 12/20 | 1.00 |
| ▸ | LGALS9 | O00182 | 6/20 | 1.00 |
| ▸ | LGALS7; LGALS7B | P47929 | 6/20 | 1.00 |
| ▸ | LGALS1 | P09382 | 6/20 | 1.00 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.69 |
| ▸ | HK1 | P19367 | 2/20 | 0.48 |
| ▸ | HK2 | P52789 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595414 | 1.00 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL2431420 | 1.00 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL22243318 | 1.00 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL2431423 | 1.00 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL16234119 | 1.00 | LGALS3 (1.00) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL19976150 | 0.95 | LGALS3 (0.90) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL17681081 | 0.94 | LGALS3 (0.88) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL17414604 | 0.91 | LGALS3 (0.84) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL14439460 | 0.91 | LGALS3 (0.84) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 | |
| SCHEMBL19976146 | 0.87 | LGALS3 (0.76) | LGALS3LGALS9LGALS7; LGALS7BLGALS1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2919802-A1 | METHODS, COMPOSITIONS AND KITS FOR TREATING, MODULATING, OR PREVENTING OCULAR ANGIOGENESIS OR FIBROSIS IN A SUBJECT USING A GALECTIN PROTEIN INHIBITOR | Tufts University (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078655-A1 | METHODS, COMPOSITIONS AND KITS FOR TREATING, MODULATING, OR PREVENTING OCULAR ANGIOGENESIS OR FIBROSIS IN A SUBJECT USING A GALECTIN PROTEIN INHIBITOR | TUFTS UNIVERSITY (US) | 2014-05-22 | — | — | WO | disclosed |