Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720476 | 1.00 | ALDH1A1 (0.31) | ALDH1A1LMNARECQLTSHRHTT | |
| SCHEMBL6766783 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL23293739 | 0.74 | — | — | |
| SCHEMBL15253834 | 0.74 | — | — | |
| SCHEMBL771653 | 0.70 | — | — | |
| SCHEMBL14856014 | 0.69 | KDM4E (0.47) | ALDH1A1LMNA | |
| SCHEMBL14914893 | 0.69 | KDM4E (0.47) | ALDH1A1LMNA | |
| SCHEMBL31498911 | 0.68 | — | — | |
| SCHEMBL2350174 | 0.67 | — | — | |
| SCHEMBL793443 | 0.66 | ALDH1A1 (0.37) | ALDH1A1LMNARECQLTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925749-A1 | DIHYDROPYRAZOLE GPR40 MODULATORS | Bristol-Myers Squibb Company (US) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014078611-A1 | DIHYDROPYRAZOLE GPR40 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-22 | — | — | WO | disclosed |