Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720329 | 0.79 | MAPT (0.36) | ALDH1A1NPC1RAB9AMEN1HPGD | |
| SCHEMBL15516657 | 0.77 | TSHR (0.40) | ALDH1A1MAPTCYP3A4CYP19A1MAPK1 | |
| SCHEMBL16106194 | 0.77 | TSHR (0.40) | ALDH1A1MAPTCYP3A4CYP19A1MAPK1 | |
| SCHEMBL16931587 | 0.77 | TSHR (0.40) | ALDH1A1MAPTCYP3A4CYP19A1MAPK1 | |
| SCHEMBL15721091 | 0.77 | TSHR (0.40) | ALDH1A1MAPTCYP3A4CYP19A1MAPK1 | |
| SCHEMBL15517115 | 0.77 | TSHR (0.40) | ALDH1A1MAPTCYP3A4CYP19A1MAPK1 | |
| SCHEMBL15720955 | 0.76 | CYP3A4 (0.41) | ALDH1A1NPC1RAB9AMEN1HPGD | |
| SCHEMBL15720832 | 0.76 | MAPT (0.45) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL10820381 | 0.75 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AMEN1HPGD | |
| SCHEMBL15071344 | 0.71 | KDM4E (0.41) | ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925742-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2016-10-26 | — | — | EP | disclosed |
| EP-2925742-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014076484-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-05-22 | — | — | WO | disclosed |