Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AMPD1 | P23109 | 2/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722729 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL15722749 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL15722788 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL15722731 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL15722787 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL13227914 | 1.00 | MAPT (0.47) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL15722750 | 0.98 | MAPT (0.49) | MAPTNPSR1TLR8ALDH1A1TDP1 | |
| SCHEMBL5929136 | 0.92 | MAPT (0.50) | MAPTNPSR1TLR8ALDH1A1KMT2A | |
| SCHEMBL15722722 | 0.84 | MAPT (0.53) | MAPTNPSR1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL10915311 | 0.84 | ALDH1A1 (0.46) | TLR8ALDH1A1TDP1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | PCNA, ITPA, MPI | MAPT 3727/4885NPSR1 1332/4885TLR8 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.