Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722765 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722763 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722769 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722762 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722810 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722809 | 0.99 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL7092926 | 0.94 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722808 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL15722761 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MITFLMNAHTT | |
| SCHEMBL25398292 | 0.81 | IDO1 (0.41) | ALDH1A1SMN1; SMN2MITFLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278951-B2 | Azolium and purinium salt anticancer and antimicrobial agents | THE UNIVERSITY OF AKRON (US) | 2016-03-08 | — | — | US | disclosed |
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | THE UNIVERSITY OF AKRON | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142307-A1 | AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS | PCNA, ITPA, MPI | ALDH1A1 3117/4885SMN1; SMN2 3715/4885MITF 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.