Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820862 | 0.92 | PDE3B (0.46) | BACE1RARBFFAR4S1PR1PTGES2 | |
| SCHEMBL15725318 | 0.90 | BACE1 (0.51) | BACE1RARBFFAR4S1PR1FFAR1 | |
| SCHEMBL17249598 | 0.90 | RARB (0.46) | BACE1RARBFFAR4S1PR1FFAR1 | |
| SCHEMBL14175171 | 0.87 | RARB (0.47) | BACE1RARBFFAR4S1PR1PTGES2 | |
| SCHEMBL17614866 | 0.87 | RARB (0.47) | BACE1RARBFFAR4S1PR1PTGES2 | |
| SCHEMBL12333085 | 0.87 | RARB (0.47) | BACE1RARBFFAR4S1PR1PTGES2 | |
| SCHEMBL18724998 | 0.87 | TAAR1 (0.58) | BACE1TAAR1CYP1A2CYP2A6 | |
| SCHEMBL15725340 | 0.87 | RARB (0.50) | RARBS1PR1KIF11RARARARG | |
| SCHEMBL15725307 | 0.87 | KIF11 (0.54) | BACE1RARBFFAR4S1PR1PTGES2 | |
| SCHEMBL20209760 | 0.86 | PDE3B (0.45) | BACE1RARBFFAR4S1PR1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234136-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-9234136-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-20140138581-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20140138581-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | US | disclosed |