SCHEMBL157261

SCHEMBL157261

S=C1N=CN=C2N=CN=C12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73936 0.69
SCHEMBL6256754 0.68
SCHEMBL2733736 0.62
SCHEMBL3801963 0.61 MPO (0.36) MPO
SCHEMBL16764604 0.59
SCHEMBL4062710 0.53
SCHEMBL3999555 0.49
SCHEMBL28436575 0.31
SCHEMBL31316207 0.31
SCHEMBL31504171 0.31

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720084-A1 TUMOR REDOX-ACTIVATED 6-THIOPURINE CONTAINING DIMER COMPOUNDS MAIA Biotechnology, Inc. (US) 2026-04-08 EP claimed
CN-113164773-B 6-Mercaptopurine nucleoside analogues 廖细斌 2025-03-21 CN claimed
CN-119591543-A Bis-aminoquinolines and nano-formulations for cancer treatment 加利福尼亚大学董事会 2025-03-11 CN claimed
CN-116082339-B Method for synthesizing 6-thiopurine derivative by copper-catalyzed three-component coupling reaction 陕西师范大学 2025-02-07 CN claimed
WO-2024249682-A1 TUMOR REDOX-ACTIVATED 6-THIOPURINE CONTAINING DIMER COMPOUNDS MAIA BIOTECHNOLOGY, INC. (US) 2024-12-05 WO claimed
CN-115023418-B Bis-aminoquinolines and nano-formulations for cancer treatment 加利福尼亚大学董事会 2024-11-19 CN claimed
CN-118480030-A Cerebulin ligands and bifunctional compounds comprising same 阿尔维纳斯运营股份有限公司 2024-08-13 CN claimed
CN-114716439-B Method for synthesizing 6-thiopurine derivative by copper catalysis 陕西师范大学 2023-08-15 CN claimed
CN-116082339-A Method for synthesizing 6-thiopurine derivative by copper-catalyzed three-component coupling reaction 陕西师范大学 2023-05-09 CN claimed
CN-115023418-A Bis-aminoquinoline and nanoformulation for cancer treatment 加利福尼亚大学董事会 2022-09-06 CN claimed
WO-1997041139-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT (US) 1997-11-06 WO claimed
EP-0570514-A4 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES INC (US) 1994-08-17 EP claimed
EP-0570514-A1 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES, INC. (US) 1993-11-24 EP claimed
US-5225550-A PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US claimed
WO-1992013869-A1 METHYLENE PHOSPHONATE NUCLEOSIDE ANALOGS AND OLIGONUCLEOTIDE ANALOGS MADE THEREFROM GILEAD SCIENCES, INC. (US) 1992-08-20 WO claimed
EP-0406309-A4 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES 1992-08-19 EP claimed
US-5126439-A Complementary purines and pyrimidines TEMPLE UNIVERSITY (US) 1992-06-30 US claimed
CN-1057652-A A kind of acyclic nucleotide of replacement and method of related intermediates thereof of preparing HOECHST AG (DE) 1992-01-08 CN claimed
EP-0406309-A1 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1991-01-09 EP claimed
WO-1989009221-A1 OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1989-10-05 WO claimed