Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464685 | 0.88 | VNN1 (0.36) | VNN1 | |
| SCHEMBL18087419 | 0.80 | SLC6A2 (0.36) | — | |
| SCHEMBL19070179 | 0.79 | — | — | |
| SCHEMBL21216310 | 0.77 | — | — | |
| SCHEMBL23841640 | 0.76 | — | — | |
| SCHEMBL18084598 | 0.76 | — | — | |
| SCHEMBL24753273 | 0.74 | — | — | |
| SCHEMBL21859845 | 0.74 | DRD4 (0.31) | — | |
| SCHEMBL21779516 | 0.73 | — | — | |
| SCHEMBL18704543 | 0.72 | VNN1 (0.34) | VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014078331-A1 | N-(ARYLALKYL)-N'-PYRAZOLYL-UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2014-05-22 | — | — | WO | disclosed |