⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12499490 | 0.97 | TDP1 (0.33) | — | |
| SCHEMBL24385086 | 0.85 | — | — | |
| SCHEMBL10058200 | 0.83 | — | — | |
| SCHEMBL27532234 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL9743519 | 0.78 | HTR2A (0.36) | — | |
| SCHEMBL16297571 | 0.77 | — | — | |
| SCHEMBL1024914 | 0.71 | — | — | |
| SCHEMBL2429787 | 0.71 | — | — | |
| SCHEMBL26229152 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL19850262 | 0.69 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111154035-B | Tree-shaped molecular imprinting material and preparation method and application thereof | 深圳市易瑞生物技术股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| US-9573934-B2 | Methods and compositions for the synthesis of multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | claimed |
| US-20150148543-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-28 | — | — | US | claimed |
| US-9024028-B2 | Methods and compositions for the synthesis of multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2015-05-05 | — | — | US | claimed |
| US-20140171649-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | ARIAD PHARMACEUTICALS, INC. (US) | 2014-06-19 | — | — | US | claimed |
| WO-2012103279-A2 | METHODS AND COMPOSITIONS FOR THE SYNTHESIS OF MULTIMERIZING AGENTS | ARIAD PHARMACEUTICALS, INCORPORATED (US) | 2012-08-02 | — | — | WO | claimed |
| CN-111154035-B | Tree-shaped molecular imprinting material and preparation method and application thereof | 深圳市易瑞生物技术股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-9573934-B2 | Methods and compositions for the synthesis of multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9573934-B2 | Methods and compositions for the synthesis of multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9573934-B2 | Methods and compositions for the synthesis of multimerizing agents | ARIAD PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-9120819-B2 | FGF-receptor agonist dimeric compounds | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |
| US-20150148543-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-28 | — | — | US | disclosed |
| US-20150148543-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-28 | — | — | US | disclosed |
| US-20140171649-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | ARIAD PHARMACEUTICALS, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20140171649-A1 | Methods and Compositions for the Synthesis of Multimerizing Agents | ARIAD PHARMACEUTICALS, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| WO-2012103279-A3 | METHODS AND COMPOSITIONS FOR THE SYNTHESIS OF MULTIMERIZING AGENTS | ARIAD PHARMACEUTICALS, INCORPORATED (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012103279-A2 | METHODS AND COMPOSITIONS FOR THE SYNTHESIS OF MULTIMERIZING AGENTS | ARIAD PHARMACEUTICALS, INCORPORATED (US) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012103279-A2 | METHODS AND COMPOSITIONS FOR THE SYNTHESIS OF MULTIMERIZING AGENTS | ARIAD PHARMACEUTICALS, INCORPORATED (US) | 2012-08-02 | — | — | WO | disclosed |
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| US-20090069368-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2009-03-12 | — | — | US | disclosed |