Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4514108 | 0.92 | MAPT (0.40) | MAPTBAZ2BBAZ2ASMN1; SMN2TP53 | |
| SCHEMBL1573132 | 0.91 | MAPT (0.40) | MAPTTP53FNTAFNTB | |
| SCHEMBL322335 | 0.85 | MAPT (0.45) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL145931 | 0.82 | HTT (0.45) | MAPTSMN1; SMN2FNTAFNTB | |
| SCHEMBL4521306 | 0.82 | MAPT (0.40) | MAPTSMN1; SMN2TP53 | |
| SCHEMBL3954660 | 0.81 | HTT (0.44) | MAPTSMN1; SMN2FNTAFNTB | |
| SCHEMBL3597910 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2TP53 | |
| Water SCHEMBL4620128 | 0.81 | HTT (0.43) | MAPTSMN1; SMN2FNTAFNTB | |
| SCHEMBL27758529 | 0.80 | MAPT (0.45) | MAPTBAZ2BBAZ2ASMN1; SMN2 | |
| SCHEMBL1573394 | 0.78 | MAPT (0.38) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |