⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26793982 | 1.00 | — | — | |
| SCHEMBL4847148 | 0.77 | — | — | |
| Meparfynol SCHEMBL547715 | 0.75 | — | — | |
| Meparfynol SCHEMBL12864498 | 0.75 | — | — | |
| Meparfynol SCHEMBL78626 | 0.75 | — | — | |
| SCHEMBL25296087 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL5069540 | 0.73 | — | — | |
| SCHEMBL12590808 | 0.73 | — | — | |
| Meparfynol SCHEMBL11215486 | 0.73 | — | — | |
| SCHEMBL5252984 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110951451-A | Packaging adhesive for LED and preparation method thereof | 肇庆皓明有机硅材料有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-3250571-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2022-11-30 | — | — | EP | disclosed |
| CN-215939918-U | System for coproduction methyl butynol and dimethyl hexynol | 北京国联视讯信息技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3954679-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3409667-B1 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | GILEAD SCIENCES INC (US) | 2021-07-21 | — | — | EP | disclosed |
| US-20210009555-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2021-01-14 | — | — | US | disclosed |
| CN-110951451-A | Packaging adhesive for LED and preparation method thereof | 肇庆皓明有机硅材料有限公司 | 2020-04-03 | — | — | CN | disclosed |
| US-10202378-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| EP-3409667-A1 | AMIDE COMPOUNDS FOR THE TREATMENT OF HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2018-12-05 | — | — | EP | disclosed |
| US-20180273508-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2018-09-27 | — | — | US | disclosed |
| WO-2012159959-A1 | 2-AMINO-3-(IMIDAZOL-2-YL)-PYRIDIN-4-ONE DERIVATIVES AND THEIR USE AS VEGF RECEPTOR KINASE INHIBITORS | SANOFI (FR) | 2012-11-29 | — | — | WO | disclosed |
| EP-2524915-A1 | 2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| EP-2158201-B1 | DERIVATIVES OF 7-ALKYNYL-1,8-NAPHTHYRIDONES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| US-20100144757-A1 | DERIVATIVES OF 7-ALKYNYL-1,8-NAPHTHYRIDONES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-2158201-A2 | DERIVATIVES OF 7-ALKYNYL-1,8-NAPHTHYRIDONES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2010-03-03 | — | — | EP | disclosed |
| WO-2009007535-A2 | DERIVATIVES OF 7-ALKYNYL-1,8-NAPHTHYRIDONES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |
| US-7053141-B2 | Organosilicone compounds having alkynol groups and the use thereof in crosslinkable materials | WACKER-CHEMIE GMBH (DE) | 2006-05-30 | — | — | US | disclosed |
| US-20060084744-A1 | Silicone rubber composition comprising untreated aluminum hydroxide as filler | WACKER-CHEMIE GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
| US-20040116566-A1 | Organosilicone compounds having alkynol groups and the use thereof in crosslinkable materials | WACKER-CHEMIE GMBH (DE) | 2004-06-17 | — | — | US | disclosed |
| US-4057596-A | POLYSILOXANE | SHINETSU CHEMICAL COMPANY (JA) | 1977-11-08 | — | — | US | disclosed |