Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL9473942 | 1.00 | TSHR (0.60) | — | |
| Benzene SCHEMBL29838040 | 0.89 | — | — | |
| Benzene SCHEMBL11765474 | 0.80 | TSHR (0.60) | — | |
| Benzene SCHEMBL8845787 | 0.80 | TSHR (0.60) | — | |
| Benzene SCHEMBL3999894 | 0.80 | — | — | |
| Benzene SCHEMBL23388152 | 0.80 | TSHR (0.60) | — | |
| Benzene SCHEMBL11683754 | 0.80 | TSHR (0.60) | — | |
| Benzene SCHEMBL23388154 | 0.80 | TSHR (0.60) | — | |
| Benzene SCHEMBL14954002 | 0.80 | — | — | |
| Benzene SCHEMBL21247178 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260036897-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | ZEISS CARL SMT GMBH (DE) | 2026-02-05 | — | — | US | claimed |
| WO-2024223530-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | CARL ZEISS SMT GMBH (DE) | 2024-10-31 | — | — | WO | claimed |
| CN-109195937-A | Acetic acid and hydrogen are generated in water-bearing media by ethyl alcohol and acetaldehyde by organic/inorganic catalyst | 沙特基础工业全球技术公司 | 2019-01-11 | — | — | CN | claimed |
| WO-2017208098-A1 | PRODUCTION OF ACETIC ACID AND HYDROGEN IN AN AQUEOUS MEDIUM FROM ETHANOL AND ACETALDEHYDE VIA AN ORGANIC/INORGANIC CATALYST | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-12-07 | — | — | WO | claimed |
| CN-104450864-A | Composition and application thereof | SINOCARE INC | 2015-03-25 | — | — | CN | claimed |
| US-20260036897-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | ZEISS CARL SMT GMBH (DE) | 2026-02-05 | — | — | US | disclosed |
| WO-2024223530-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | CARL ZEISS SMT GMBH (DE) | 2024-10-31 | — | — | WO | disclosed |
| WO-2023026860-A1 | HYDROGEN PRODUCTION METHOD | 日東電工株式会社 | 2023-03-02 | — | — | WO | disclosed |
| CN-115667242-A | Tetrahydroisoquinoline compounds as NRF2 activators | 希四克斯探索有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-3094318-B1 | NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS AND THEIR METHOD OF USE FOR THE TREATMENT OF HEPATIC ENCEPHALOPATHY | KANNALIFE SCIENCES INC (US) | 2020-02-19 | — | — | EP | disclosed |
| US-20190315672-A1 | PRODUCTION OF ACETIC ACID AND HYDROGEN IN AN AQUEOUS MEDIUM FROM ETHANOL AND ACETALDEHYDE VIA AN ORGANIC/INORGANIC CATALYST | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-17 | — | — | US | disclosed |
| CN-109195937-A | Acetic acid and hydrogen are generated in water-bearing media by ethyl alcohol and acetaldehyde by organic/inorganic catalyst | 沙特基础工业全球技术公司 | 2019-01-11 | — | — | CN | disclosed |
| WO-2004084834-A2 | CHIRAL POROUS METAL PHOSPHONATES FOR HETEROGENEOUS ASYMMETRIC CATALYSIS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040192543-A1 | Chiral porous metal phosphonates for heterogeneous asymmetric catalysis | NORTH CAROLINA AT CHAPEL HILL, UNIVERSITY OF, THE | 2004-09-30 | — | — | US | disclosed |
| WO-2003095420-A1 | HYDROXY TETRAHYDRO-NAPHTHALENYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| US-20030045727-A1 | Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1254885-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS HAVING NITROGENOUS OR OXYGENIC FUNCTIONAL GROUPS | Asahi Kasei Kabushiki Kaisha (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5399722-A | Process for preparing tert-butyl (3R,5S)-6-hydroxy-3,5--O--isopropylidene-3,5-dihydroxyhexanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| US-5204460-A | Reacting azetidinone compound with acetic acid and oxidizing agent in the presence of ruthenium catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-04-20 | — | — | US | disclosed |
| US-4504674-A | METAL TREATED RUTHENIUM CATALYST | E. I. DUPONT DE NEMOURS & CO. (US) | 1985-03-12 | — | — | US | disclosed |