SCHEMBL15729822

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15708839	0.98	KMT2A (0.42)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL15726640	0.91	KMT2A (0.38)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL15708320	0.91	KMT2A (0.53)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL15726608	0.89	KMT2A (0.36)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL2577691	0.84	CYP3A4 (0.44)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL16270514	0.84	PRSS1 (0.43)	KMT2ACYP3A4TSHRPRSS1PRSS2
	SCHEMBL16270524	0.83	GAA (0.51)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL28493468	0.81	BCL9 (0.53)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL15708348	0.81	CYP3A4 (0.42)	KMT2ALMNAALDH1A1MAPTHTT
	SCHEMBL15726604	0.81	KMT2A (0.44)	KMT2ALMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.