Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498647 | 0.93 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL150004 | 0.92 | MAPT (0.46) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL1573171 | 0.89 | NR1H4 (0.42) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL13918682 | 0.89 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL1573253 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL4518702 | 0.88 | MEN1 (0.38) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL1573416 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL1573017 | 0.86 | F10 (0.39) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL1573409 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL13918726 | 0.85 | F10 (0.38) | MEN1KMT2AALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2018165-A1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | Sanofi-Aventis (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007080325-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2007-07-19 | — | — | WO | disclosed |