Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721274 | 0.97 | EPHX2 (0.48) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL1122001 | 0.92 | EPHX2 (0.53) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL1573160 | 0.90 | SMN1; SMN2 (0.47) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL466108 | 0.87 | SMN1; SMN2 (0.49) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL3764756 | 0.86 | LMNA (0.50) | SMN1; SMN2LMNA | |
| SCHEMBL22367410 | 0.83 | SMN1; SMN2 (0.53) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL1572844 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNA | |
| SCHEMBL24674898 | 0.81 | MAPT (0.51) | EPHX2SMN1; SMN2HTTTSHRL3MBTL1 | |
| SCHEMBL24756824 | 0.80 | SMN1; SMN2 (0.53) | EPHX2SMN1; SMN2LMNATEAD3HTT | |
| SCHEMBL291194 | 0.80 | SMN1; SMN2 (0.57) | EPHX2SMN1; SMN2TEAD3HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814523-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING A MULTI-ARM PEG MACROMER | NOVARTIS AG (CH) | 2016-04-06 | — | — | EP | claimed |
| EP-2470578-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | NOVARTIS AG (CH) | 2014-11-12 | — | — | EP | claimed |
| EP-2192933-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON INC (CH) | 2011-05-25 | — | — | EP | claimed |
| EP-2192932-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON INC (CH) | 2011-05-04 | — | — | EP | claimed |
| EP-2192931-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYLPHENOL ETHOXYLATE | ALCON INC (CH) | 2011-05-04 | — | — | EP | claimed |
| EP-2192934-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON INC (CH) | 2011-05-04 | — | — | EP | claimed |
| EP-2192930-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING AN ALKYL ETHOXYLATE | ALCON INC (CH) | 2011-04-13 | — | — | EP | claimed |