Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | GJA1 | P17302 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.46 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.46 |
| ▸ | FGF1 | P05230 | 1/20 | 0.46 |
| ▸ | FGF2 | P09038 | 1/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526345 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL5514966 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL20034302 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL16316509 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL4260234 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL6415085 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL6820046 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL4285005 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL4280409 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 | |
| SCHEMBL4284998 | 1.00 | LGALS8 (0.56) | LGALS8MEN1KMT2ACD209LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140141034-A1 | TYROSINE LIGATION PROCESS | NOVARTIS AG (CH) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140141034-A1 | TYROSINE LIGATION PROCESS | ACP1, LTK, TTL | LGALS8 376/4885MEN1 1156/4885KMT2A 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.