SCHEMBL15733416

SCHEMBL15733416

CO[Si](O)(O)c1ccc(-c2cc(F)cc(F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 4/20 0.35
ABCC1 P33527 2/20 0.35
CYP17A1 P05093 2/20 0.34
CYP21A2 P08686 2/20 0.34
CYP11B1 P15538 2/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
KIT P10721 1/20 0.33
PGR P06401 1/20 0.33
MAP4K4 O95819 1/20 0.33
ABL1 P00519 1/20 0.32
BCR P11274 1/20 0.32
ESR2 Q92731 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735145 0.86 NPC1 (0.38) NPC1CASP3RAB9ASMN1; SMN2SENP8
SCHEMBL15734638 0.85 ABCB1 (0.35) ABCB1ABCC1CYP17A1CYP21A2CYP11B1
SCHEMBL15735452 0.84 ESR2 (0.53) CYP17A1CYP11B1PGRMAP4K4ESR2
SCHEMBL15734489 0.84 ANPEP (0.36) ABCB1CYP17A1CYP11B1ABL1BCR
SCHEMBL15733761 0.82 ESR1 (0.32) ESR2
SCHEMBL15734438 0.81 ABCB1 (0.36) ABCB1ABCC1CYP17A1CYP21A2CYP11B1
SCHEMBL15734829 0.80 CYP11B1 (0.41) CYP17A1CYP11B1PGRNOTUMPDGFRB
SCHEMBL27959505 0.80 CA12 (0.36)
SCHEMBL15737187 0.80 ACHE (0.36) NPC1MAPK1CASP3RAB9ASMN1; SMN2
SCHEMBL15736965 0.79 CYP17A1 (0.35) ABCB1ABCC1CYP17A1CYP21A2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed