SCHEMBL15733441

SCHEMBL15733441

CC(C)O[Si](O)(OC(C)C)c1ccc(-c2ccc(F)cc2F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
HIF1A Q16665 2/20 0.38
SLC22A6 Q4U2R8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
DHFR P00374 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TTR P02766 1/20 0.38
ALB P02768 1/20 0.38
HMGB1 P09429 1/20 0.38
CXCL12 P48061 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
HSD17B10 Q99714 1/20 0.38
AKR1C3 P42330 4/20 0.37
AKR1C2 P52895 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733807 0.85 ALOX5AP (0.37) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15735472 0.85 TRPV3 (0.34) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15738187 0.83 TTR (0.41) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15734699 0.82 CYP17A1 (0.35) CYP3A4MAPTGCGR
SCHEMBL15735289 0.82 MAPK14 (0.30) GCGR
SCHEMBL15733609 0.81 MEN1 (0.42) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15734543 0.81 APP (0.36) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15734663 0.81 APP (0.36) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL15733851 0.81 MAPT (0.36) KMT2ALMNAALDH1A1MAPT
SCHEMBL15734903 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed
US-20130143826-A1 CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) 2013-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143826-A1 CHEMICAL SYNTHESIS AND ANTI-TUMOR AND ANTI-METASTATIC EFFECTS OF DUAL FUNCTIONAL CONJUGATE PTMS, DNPEP, PAICS MEN1 687/4885KMT2A 3430/4885LMNA 3784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.