SCHEMBL15734656

SCHEMBL15734656

CCO[Si](OC)(OC)c1ccc(-c2cc(F)cc(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.35
FGFR2 P21802 1/20 0.35
CYP17A1 P05093 2/20 0.34
CYP21A2 P08686 2/20 0.34
CYP11B1 P15538 2/20 0.34
ABCB1 P08183 2/20 0.32
ABCC1 P33527 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
BACE1 P56817 1/20 0.30
CYP1A2 P05177 1/20 0.30
GSK3B P49841 1/20 0.30
KIT P10721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737093 0.97 FGFR1 (0.35) FGFR1FGFR2CYP17A1CYP21A2CYP11B1
SCHEMBL15737558 0.92 FGFR1 (0.38) FGFR1FGFR2CYP17A1CYP21A2CYP11B1
SCHEMBL15733585 0.88 NPC1 (0.37) CYP17A1CYP1A2
SCHEMBL15735017 0.86 TAAR1 (0.45) CYP17A1CYP11B1
SCHEMBL15734438 0.86 ABCB1 (0.36) CYP17A1CYP21A2CYP11B1ABCB1ABCC1
SCHEMBL15738173 0.86 CYP17A1 (0.33) CYP17A1CYP11B1
SCHEMBL15733811 0.85 NPC1 (0.34) CYP17A1CYP1A2
SCHEMBL15735621 0.84 FGFR1 (0.32) FGFR1FGFR2
SCHEMBL15738026 0.83 TAAR1 (0.45) CYP17A1CYP11B1
SCHEMBL15737129 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed