SCHEMBL15735017

SCHEMBL15735017

CCO[Si](OC)(OC)c1ccc(-c2cccc(F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
ESR2 Q92731 1/20 0.44
CYP11B2 P19099 2/20 0.43
CYP17A1 P05093 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP11B1 P15538 1/20 0.43
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
PTPN1 P18031 1/20 0.38
FYN P06241 2/20 0.38
GRM5 P41594 1/20 0.37
HTR2C P28335 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
NT5E P21589 2/20 0.35
FFAR1 O14842 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738026 0.97 TAAR1 (0.45) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15735356 0.92 TAAR1 (0.49) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15738543 0.88 TAAR1 (0.52) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15734656 0.86 FGFR1 (0.35) CYP17A1CYP11B1
SCHEMBL15733585 0.84 NPC1 (0.37) CYP17A1PDGFRBPDGFRAFYNTRPM8
SCHEMBL15737093 0.83 FGFR1 (0.35) CYP17A1CYP11B1
SCHEMBL15736859 0.83 MAOB (0.46)
SCHEMBL15734757 0.83 ACHE (0.35) TAAR1TRPM8FFAR1
SCHEMBL15733738 0.82 TAAR1 (0.47) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15733734 0.82 CYP11B1 (0.41) CYP11B2CYP17A1CYP11B1PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed