SCHEMBL1573476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13893331	0.89	NOTUM (0.54)	NOTUMCYP2C9CYP2C19FFAR2POLB
	SCHEMBL5802557	0.84	SERPINE1 (0.60)	NOTUMCYP2C9CYP2C19CYP1A2CYP3A4
	SCHEMBL18700734	0.83	FFAR4 (0.61)	NOTUMCYP2C9CYP2C19CYP1A2CYP3A4
	SCHEMBL17305261	0.83	NOTUM (0.57)	NOTUMCYP2C9CYP2C19CYP1A2CYP3A4
	SCHEMBL12644303	0.83	FFAR2 (0.62)	NOTUMCYP2C9CYP2C19CYP1A2CYP3A4
	SCHEMBL2073585	0.81	NOTUM (0.61)	NOTUM
	SCHEMBL18701232	0.81	NOTUM (0.54)	NOTUMCYP2C9CYP2C19CYP1A2CYP3A4
	SCHEMBL2072056	0.81	NOTUM (0.83)	NOTUMMAPT
	SCHEMBL2039548	0.81	MAPT (0.80)	CYP2C9CYP2C19CYP1A2CYP3A4CYP2D6
	SCHEMBL29788183	0.81	MAPT (0.80)	CYP2C9CYP2C19CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.