⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157189 | 0.94 | — | — | |
| SCHEMBL3866734 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL7994732 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL313546 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL154494 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL9514818 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL10949267 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL9515428 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL1117101 | 0.92 | PTPN7 (0.50) | — | |
| SCHEMBL1038888 | 0.92 | PTPN7 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2384 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202664-A1 | SMALL MOLECULE IL-17A MODULATORS | BEIGENE, LTD. (KY) | 2023-10-26 | — | — | WO | claimed |
| US-20120232105-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING OSTEOCLAST GROWTH | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-09-13 | — | — | US | claimed |
| US-20040171839-A1 | Polycyclic aryl and heteroaryl substituted 1, 4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-09-02 | — | — | US | claimed |
| US-20040171616-A9 | Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-09-02 | — | — | US | claimed |
| US-20040162319-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-08-19 | — | — | US | claimed |
| US-20040138275-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-07-15 | — | — | US | claimed |
| JP-2004505014-A | — | — | 2004-02-19 | — | — | JP | claimed |
| US-20040006227-A1 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-01-08 | — | — | US | claimed |
| US-20030236257-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | claimed |
| US-20030236231-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | claimed |
| US-20020025947-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-02-28 | — | — | US | claimed |
| US-20020022604-A1 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade | PHAMACIA CORPORATION | 2002-02-21 | — | — | US | claimed |
| US-20020010344-A1 | Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-01-24 | — | — | US | claimed |
| WO-2001079155-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 1,4-QUINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001077079-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-10-18 | — | — | WO | claimed |
| WO-2001077097-A2 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED 4-PYRONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-10-18 | — | — | WO | claimed |
| WO-2001068605-A1 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-09-20 | — | — | WO | claimed |
| US-20010018446-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2001-08-30 | — | — | US | claimed |
| US-5192767-A | Nonphytotoxic | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | claimed |
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | claimed |