SCHEMBL15734848

SCHEMBL15734848

CC(C)(O[SiH3])c1ccc(-c2cc(F)c(F)cc2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.38
AKR1C3 P42330 4/20 0.35
AKR1C2 P52895 4/20 0.35
PTGS2 P35354 10/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 3/20 0.32
GYS1 P13807 1/20 0.31
KIF11 P52732 1/20 0.31
SCD O00767 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15736926 0.83 APP (0.33) APPAKR1C3AKR1C2
SCHEMBL15736768 0.83 APP (0.42) APPAKR1C3AKR1C2PTGS2CYP3A4
SCHEMBL28156905 0.82 AKR1C3 (0.36) APPAKR1C3AKR1C2PTGS2
SCHEMBL15735778 0.81 CYP17A1 (0.41) KIF11
SCHEMBL15738775 0.79 APP (0.35) APPAKR1C3AKR1C2PTGS2CYP3A4
SCHEMBL15738456 0.79 PTGS2 (0.34) APPAKR1C3AKR1C2PTGS2PTGS1
SCHEMBL15737758 0.77 ANPEP (0.37) KIF11
SCHEMBL15734392 0.76 AKR1C3 (0.35) APPAKR1C3AKR1C2
SCHEMBL15734461 0.76 APP (0.31) APPGYS1
SCHEMBL15738982 0.76 TNKS (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed