SCHEMBL1573573

SCHEMBL1573573

N#Cc1c(O)c(C#N)c(Cl)c(O)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.48
HPGD P15428 3/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.42
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3462600 0.92 HPGD (0.47) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL8885184 0.88 MEN1 (0.63) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL28811328 0.83 MEN1 (0.43) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL11753654 0.82 HPGD (0.63) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL11752918 0.80 MEN1 (0.60) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL1573448 0.79 MEN1 (0.50) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL29842862 0.79 MEN1 (0.50) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL8886111 0.78 MEN1 (0.65) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL9244159 0.77 MEN1 (0.55) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL5164401 0.74 MEN1 (0.40) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1492092-B1 Two-photon absorbing optical recording material and two-photon absorbing optical recording and reproducing method FUJIFILM CORP (JP) 2011-04-13 EP disclosed
US-20100239962-A1 TWO-PHOTON ABSORBING OPTICAL RECORDING MATERIAL AND TWO-PHOTON ABSORBING OPTICAL RECORDING AND REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-7771915-B2 Two-photon absorbing optical recording material and two-photon absorbing optical recording and reproducing method FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
EP-2180467-A1 Photon-mode recording method Fujifilm Corporation (JP) 2010-04-28 EP disclosed
US-20090303855-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2009-12-10 US disclosed
US-7588863-B2 Hologram recording method and hologram recording material FUJIFILM CORPORATION (JP) 2009-09-15 US disclosed
US-7582390-B2 Two-photon absorbing polymerization method, two-photon absorbing optical recording material and two-photon absorbing optical recording method FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7582391-B2 Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060083890-A1 Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-04-20 US disclosed
US-20060057467-A1 Hologram recording material and hologram recording method FUJI PHOTO FILM CO., LTD. 2006-03-16 US disclosed
US-20050058910-A1 Hologram recording method and hologram recording material FUJI PHOTO FILM CO., LTD. 2005-03-17 US disclosed
US-20050046915-A1 Hologram recording material composition, hologram recording material and hologram recording method FUJI PHOTO FILM CO., LTD. 2005-03-03 US disclosed
EP-1510862-A2 Hologram recording method and hologram recording material Fuji Photo Film Co., Ltd. (JP) 2005-03-02 EP disclosed
EP-1508833-A2 Hologram recording material composition, hologram recording material and hologram recording method FUJI PHOTO FILM CO., LTD. (JP) 2005-02-23 EP disclosed
US-20050003133-A1 Two-photon absorbing optical recording material and two-photon absorbing optical recording and reproducing method FUJI PHOTO FILM CO., LTD. 2005-01-06 US disclosed
US-20040245432-A1 Two-photon absorbing polymerization method, two-photon absorbing optical recording material and two-photon absorbing optical recording method FUJI PHOTO FILM CO., LTD. 2004-12-09 US disclosed