SCHEMBL9244159

SCHEMBL9244159

N#Cc1c(O)c(C#N)c(C#N)c(O)c1C#N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
CACNA1B Q00975 1/20 0.55
APBA1 Q02410 1/20 0.55
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TTR P02766 2/20 0.35
ALB P02768 2/20 0.35
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452430 0.96 MEN1 (0.52) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL9576714 0.80 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL1573448 0.79 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL10379756 0.79 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL29842862 0.79 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL5162118 0.79 ALDH1A1 (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL1573573 0.77 MEN1 (0.48) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL28474495 0.77 KDM4E (0.39) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL10876678 0.75 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL21929108 0.73 KDM4E (0.36) MEN1KMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118284110-A Photoelectric device, preparation method thereof and display device TCL科技集团股份有限公司 2024-07-02 CN claimed
CN-118732427-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2024-10-01 CN disclosed
CN-118284110-A Photoelectric device, preparation method thereof and display device TCL科技集团股份有限公司 2024-07-02 CN disclosed
CN-116102460-B Quaternary spectrum organic eutectic material based on tetracyano-terephthalquinone and application thereof in water evaporation 天津大学 2023-09-15 CN disclosed
CN-116102460-A Quaternary spectrum organic eutectic material based on tetracyano-terephthalquinone and application thereof in water evaporation 天津大学 2023-05-12 CN disclosed
CN-110234515-B Recording material and recording sheet 日本曹达株式会社 2022-02-11 CN disclosed
EP-0684044-A2 Composition consisting of a dendrimer and an active substance DSM N.V. (NL) 1995-11-29 EP disclosed
US-4571435-A SUSTAINED RELEASE TENNESSEE VALLEY AUTHORITY (US) 1986-02-18 US disclosed
US-4379939-A Preparation of nitrogen fertilizers from oxalate esters prepared by the oxidative carbonylation of alcohols over noble metal catalysts utilizing regenerable 2,5-cyclohexadiene-1,4-dione oxidants TENNESSEE VALLEY AUTHORITY (US) 1983-04-12 US disclosed