SCHEMBL15735862

SCHEMBL15735862

CC(C)(O[SiH3])c1cccc(-c2c(F)c(F)c(F)c(F)c2F)c1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
IKBKB O14920 1/20 0.33
BRD4 O60885 1/20 0.33
PTPN1 P18031 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CNR2 P34972 2/20 0.32
CNR1 P21554 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
PTPN5 P54829 1/20 0.31
MAPK1 P28482 1/20 0.31
TGFBR1 P36897 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
DHODH Q02127 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737271 0.80 SLC1A3 (0.36) SLC1A3SLC1A2SLC1A1IKBKBBRD4
SCHEMBL15734107 0.80 SLC1A3 (0.34) SLC1A3SLC1A2SLC1A1IKBKBBRD4
SCHEMBL15735455 0.79 MAPK1 (0.30) MAPK1
SCHEMBL15738720 0.77 SLC1A3 (0.33) SLC1A3SLC1A2SLC1A1IKBKBBRD4
SCHEMBL15738214 0.77 SLC1A3 (0.33) SLC1A3SLC1A2SLC1A1IKBKBBRD4
SCHEMBL15735429 0.77 KCNN4 (0.43) KIF11PTPN1MAPK1
SCHEMBL17563223 0.74 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1IKBKBBRD4
SCHEMBL15737030 0.73 DHODH (0.33) DHODH
SCHEMBL15736194 0.73 TSHR (0.45) MAPK1
SCHEMBL15734494 0.72 MAOB (0.48) KIF11RXRARXRBPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed
US-20120267574-A1 MATERIALS FOR OPTOELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2012-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120267574-A1 MATERIALS FOR OPTOELECTRONIC DEVICES SCO2, ORC3, C1S KIF11 2404/4885SLC1A3 2292/4885SLC1A2 2517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.