SCHEMBL15735429

SCHEMBL15735429

CC(C)(O[SiH3])c1cccc(F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.43
ACHE P22303 1/20 0.40
KIF11 P52732 1/20 0.37
CYP19A1 P11511 2/20 0.36
MAPK1 P28482 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NFE2L2 Q16236 2/20 0.34
ALDH1A1 P00352 2/20 0.33
PTPN1 P18031 1/20 0.33
CHRM3 P20309 1/20 0.33
IDO1 P14902 1/20 0.33
AGXT P21549 1/20 0.33
ALOX15 P16050 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
MDM4 O15151 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738692 0.80 PTPN1 (0.49) PTPN1AGXT
SCHEMBL15736194 0.80 TSHR (0.45) MAPK1NFE2L2ALDH1A1IDO1NPSR1
SCHEMBL15736526 0.79 CA12 (0.31)
SCHEMBL15735862 0.77 KIF11 (0.34) KIF11MAPK1PTPN1
SCHEMBL7929172 0.76 KCNN4 (0.50) KCNN4ACHEKIF11CYP19A1HDAC3
SCHEMBL179310 0.76 KCNN4 (0.50) KCNN4ACHEKIF11CYP19A1HDAC3
SCHEMBL2441745 0.76 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TP53POLB
SCHEMBL15734515 0.76 KCNN4 (0.47) KCNN4ACHEKIF11CYP19A1NFE2L2
SCHEMBL15734383 0.76 KCNN4 (0.40) KCNN4ACHEKIF11CYP19A1CHRM3
SCHEMBL1793024 0.76 KCNN4 (0.51) KCNN4ACHEHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed