Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034185 | 0.86 | KDM4E (0.38) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30837415 | 0.80 | — | — | |
| SCHEMBL29181146 | 0.80 | — | — | |
| SCHEMBL3254805 | 0.80 | — | — | |
| SCHEMBL6970710 | 0.80 | — | — | |
| SCHEMBL2759539 | 0.80 | — | — | |
| SCHEMBL20048805 | 0.80 | — | — | |
| SCHEMBL11539596 | 0.80 | ALDH1A1 (0.34) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL5082430 | 0.78 | KDM4E (0.39) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL9098260 | 0.78 | PDPK1 (0.36) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049527-A2 | PREPARATION OF IRBESARTAN | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-04-22 | — | — | EP | claimed |
| WO-2006073376-A2 | PREPARATION OF IRBESARTAN | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2006-07-13 | — | — | WO | claimed |
| JP-3086862-A | — | — | None | — | — | JP | disclosed |
| CN-110678458-A | Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders | 武田药品工业株式会社 | 2020-01-10 | — | — | CN | disclosed |
| CN-105541796-A | Synthetic method of NH-1,2,3-triazole bipyridine compounds | WUHAN INST TECHNOLOGY | 2016-05-04 | — | — | CN | disclosed |
| CN-103709144-A | Pyrimidine derivatives substituted picolyl sulfoxide compound and preparation method thereof | ANHUI COSTAR BIO CHEMICAL CO LTD | 2014-04-09 | — | — | CN | disclosed |
| CN-103524494-A | Sulfydryl imidazole derivative comprising picoline group and synthetic method | ANHUI COSTAR BIO CHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-103524494-A | Sulfydryl imidazole derivative comprising picoline group and synthetic method | ANHUI COSTAR BIO CHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| EP-1548005-B1 | PROCESS FOR PRODUCING 2-SUBSTITUTED PYRIDINE DERIVATIVE | KURARAY CO (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-7560563-B2 | Process for producing 2-substituted pyridine derivative | KURARAY CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| EP-2049527-A2 | PREPARATION OF IRBESARTAN | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-04-22 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
| US-6169184-B1 | REACTING SUBSTITUTED PYRIDINE WITH SPECIFIED ARYL COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |
| CN-1230181-A | Process for preparing substituted phenylpyridines | BASF AG (DE) | 1999-09-29 | — | — | CN | disclosed |
| EP-0931068-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998011069-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
| EP-0795023-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996017075-A1 | A PROCESS FOR PRODUCING SULPHOXIDE ENRICHED IN THE (R) OR THE (S) ENANTIOMER | ZENECA LIMITED (GB) | 1996-06-06 | — | — | WO | disclosed |
| JP-H0386862-A | NOVEL PROCESS FOR PRODUCING BIPYRIDINE DERIVATIVE | WAKO PURE CHEM IND LTD | 1991-04-11 | — | — | JP | disclosed |
| CN-87103523-A | The 5-sulfur substituted pyriding monocarboxylic herbicides | — | 1987-12-09 | — | — | CN | disclosed |