SCHEMBL15737458

SCHEMBL15737458

CO[Si](OC)(OC(C)C)c1ccc(-c2cc(F)cc(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 3/20 0.32
ABCC1 P33527 2/20 0.32
CYP17A1 P05093 2/20 0.31
CYP21A2 P08686 2/20 0.31
CYP11B1 P15538 2/20 0.31
FFAR4 Q5NUL3 1/20 0.30
BACE1 P56817 1/20 0.30
KIT P10721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735161 0.97 ABCB1 (0.32) ABCB1ABCC1CYP17A1CYP21A2CYP11B1
SCHEMBL15736160 0.92 CYP17A1 (0.33) CYP17A1CYP21A2CYP11B1FFAR4
SCHEMBL15734683 0.88 NPC1 (0.34) CYP17A1
SCHEMBL15735828 0.86 TAAR1 (0.44) CYP17A1CYP11B1KIT
SCHEMBL15734438 0.86 ABCB1 (0.36) ABCB1ABCC1CYP17A1CYP21A2CYP11B1
SCHEMBL15738079 0.86 ANPEP (0.34) CYP17A1CYP11B1
SCHEMBL15735022 0.85 NPC1 (0.34) CYP17A1
SCHEMBL15733929 0.84 MAPK14 (0.30)
SCHEMBL15738685 0.83 TAAR1 (0.44) CYP17A1CYP11B1KIT
SCHEMBL15738102 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed