SCHEMBL15735828

SCHEMBL15735828

CO[Si](OC)(OC(C)C)c1ccc(-c2cccc(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
ESR2 Q92731 1/20 0.44
CYP11B2 P19099 2/20 0.40
CYP17A1 P05093 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP11B1 P15538 1/20 0.40
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
PTPN1 P18031 1/20 0.38
FYN P06241 2/20 0.38
MMP1 P03956 2/20 0.37
MMP2 P08253 2/20 0.37
MMP3 P08254 2/20 0.37
MMP7 P09237 2/20 0.37
MMP9 P14780 2/20 0.37
MMP13 P45452 2/20 0.37
PGR P06401 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
NT5E P21589 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738685 0.97 TAAR1 (0.44) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15737844 0.92 TAAR1 (0.47) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15738543 0.88 TAAR1 (0.52) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15737458 0.86 ABCB1 (0.32) CYP17A1CYP11B1KIT
SCHEMBL15734683 0.84 NPC1 (0.34) CYP17A1CYP3A4PDGFRBPDGFRAFYN
SCHEMBL15735161 0.83 ABCB1 (0.32) CYP17A1CYP11B1KIT
SCHEMBL15737951 0.83 ALDH1A1 (0.43)
SCHEMBL15738314 0.83 ACHE (0.35) PDGFRBPDGFRAFYN
SCHEMBL15736626 0.82 PDGFRB (0.38) CYP11B2CYP17A1CYP3A4CYP11B1PDGFRB
SCHEMBL15735022 0.81 NPC1 (0.34) CYP17A1CYP3A4PDGFRBPDGFRAFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed