Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ARHGDIA | P52565 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574218 | 0.91 | MAPK1 (0.67) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL1573769 | 0.81 | MAPK1 (0.48) | MAPK1MAPTRAB9ANPSR1ALDH1A1 | |
| SCHEMBL1573767 | 0.81 | MAPK1 (0.48) | MAPK1MAPTRAB9ANPSR1ALDH1A1 | |
| SCHEMBL22716655 | 0.78 | MAPK1 (0.53) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL31192586 | 0.78 | MAPK1 (0.53) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL7240975 | 0.78 | MAPK1 (0.54) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL7240972 | 0.78 | MAPK1 (0.54) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL4014383 | 0.78 | MEN1 (0.56) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL6159635 | 0.76 | MAPK1 (1.00) | MAPK1MAPTRAB9APKMNPSR1 | |
| SCHEMBL3604934 | 0.76 | MAPK1 (0.52) | MAPK1MAPTRAB9APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-B1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PHIVCO UK LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |