Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573767 | 1.00 | MAPK1 (0.48) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL1573863 | 0.90 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL1573866 | 0.90 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL7236134 | 0.90 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL1573772 | 0.81 | MAPK1 (0.61) | MAPK1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL22716655 | 0.80 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL31192586 | 0.80 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 | |
| SCHEMBL1573922 | 0.80 | KDM4E (0.44) | MAPK1RAB9ANPC1GAAMAPT | |
| SCHEMBL1573923 | 0.80 | KDM4E (0.44) | MAPK1RAB9ANPC1GAAMAPT | |
| SCHEMBL31196591 | 0.79 | MAPK1 (0.53) | MAPK1HCAR3RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-B1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PHIVCO UK LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |