Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.70 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28453637 | 0.95 | — | — | |
| Bicarbonate SCHEMBL8040241 | 0.95 | — | — | |
| Bicarbonate SCHEMBL8726959 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL242848 | 0.95 | — | — | |
| Bicarbonate SCHEMBL5346453 | 0.95 | — | — | |
| Bicarbonate SCHEMBL4097336 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL4876554 | 0.95 | — | — | |
| Bicarbonate SCHEMBL8799118 | 0.95 | — | — | |
| Bicarbonate SCHEMBL457021 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL28599323 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118186446-A | Method for realizing selective electrocatalytic hydrogenation of 1, 4-butynediol by regulating copper valence state | 北京化工大学 | 2024-06-14 | — | — | CN | claimed |
| CN-115772137-B | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20230201386-A1 | PRODUCING RADIOPHARMACEUTICAL COLD KITS WITHOUT LYOPHILIZATION | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2023-06-29 | — | — | US | claimed |
| CN-115385805-A | Method for synthesizing dobutamine hydrochloride | 广州仁恒医药科技股份有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111735811-A | Triglyceride detection reagent, triglyceride detection test paper and preparation method of triglyceride detection test paper | 民康医疗科技（天津）有限公司 | 2020-10-02 | — | — | CN | claimed |
| US-20200232993-A1 | METHODS AND COMPOSITIONS FOR FLUORESCENT AND COLORIMETRIC PROTEIN QUANTITATION | PIERCE BIOTECHNOLOGY, INC. | 2020-07-23 | — | — | US | claimed |
| EP-3652543-A1 | METHODS AND COMPOSITIONS FOR FLUORESCENT AND COLORIMETRIC PROTEIN QUANTITATION | Pierce Biotechnology, Inc. (US) | 2020-05-20 | — | — | EP | claimed |
| CN-110922585-A | Method for preparing polyamide resin by utilizing double-screw extrusion reaction | 株洲时代新材料科技股份有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-110892268-A | Methods and compositions for fluorescent and colorimetric protein quantification | 皮尔斯生物科技有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-110804176-A | Method for preparing aromatic polyamide by adopting interfacial-solid phase polycondensation | 株洲时代新材料科技股份有限公司 | 2020-02-18 | — | — | CN | claimed |
| US-20030194475-A1 | Method for treating an animal carcass | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2003-10-16 | — | — | US | claimed |
| WO-2003003842-A1 | METHOD FOR TREATING AN ANIMAL CARCASS OR PLANT MATERIAL | RHODIA INC. (US) | 2003-01-16 | — | — | WO | claimed |
| EP-0621319-B1 | Pigment composition, printing ink and coating composition | TOYO INK MFG CO (JP) | 2000-06-21 | — | — | EP | claimed |
| US-5451417-A | Without proofing | VAN DEN BERGH FOODS CO., DIVISION OF CONOPCO, INC. (US) | 1995-09-19 | — | — | US | claimed |
| US-5407379-A | Differential pressure metering and dispensing system for abrasive media | CHURCH & DWIGHT CO., INC. (US) | 1995-04-18 | — | — | US | claimed |
| EP-0621319-A2 | Pigment composition, printing ink and coating composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1994-10-26 | — | — | EP | claimed |
| EP-0523181-A4 | IMPROVEMENT IN BLASTING APPARATUS | — | 1993-02-10 | — | — | EP | claimed |
| EP-0523181-A1 | IMPROVEMENT IN BLASTING APPARATUS | Church & Dwight Co., Inc. (US) | 1993-01-20 | — | — | EP | claimed |
| US-5083402-A | Blasting apparatus | CHURCH & DWIGHT CO., IND. (US) | 1992-01-28 | — | — | US | claimed |
| WO-1991015336-A1 | IMPROVEMENT IN BLASTING APPARATUS | CHURCH & DWIGHT CO., INC. (US) | 1991-10-17 | — | — | WO | claimed |