Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1573936 | 0.95 | CA4 (0.70) | — | |
| Bicarbonate SCHEMBL28601265 | 0.95 | — | — | |
| Bicarbonate SCHEMBL29038400 | 0.95 | — | — | |
| Bicarbonate SCHEMBL242848 | 0.90 | — | — | |
| Bicarbonate SCHEMBL457021 | 0.90 | CA4 (0.64) | — | |
| Bicarbonate SCHEMBL4097336 | 0.90 | CA4 (0.64) | — | |
| Bicarbonate SCHEMBL4876554 | 0.90 | — | — | |
| Bicarbonate SCHEMBL8799118 | 0.90 | — | — | |
| Bicarbonate SCHEMBL8040241 | 0.90 | — | — | |
| Bicarbonate SCHEMBL5346453 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116426946-A | High-selectivity preparation method of potential pramipexole crude drug process impurities | 德济医药科技(天津)有限责任公司 | 2023-07-14 | — | — | CN | claimed |
| CN-112979618-A | Indirubin derivative and preparation method and application thereof | 东南大学 | 2021-06-18 | — | — | CN | claimed |
| CN-116426946-A | High-selectivity preparation method of potential pramipexole crude drug process impurities | 德济医药科技(天津)有限责任公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116426946-A | High-selectivity preparation method of potential pramipexole crude drug process impurities | 德济医药科技(天津)有限责任公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112979618-A | Indirubin derivative and preparation method and application thereof | 东南大学 | 2021-06-18 | — | — | CN | disclosed |