SCHEMBL15740255

SCHEMBL15740255

Nc1ncnc2c1c(I)cn2[C@H]1C[C@@H](O)C(CO)O1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADK P55263 14/20 0.56
MTOR P42345 1/20 0.54
RAB9A P51151 1/20 0.54
TK1 P04183 1/20 0.51
HIF1A Q16665 1/20 0.50
HASPIN Q8TF76 1/20 0.50
PNP P00491 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
SLC29A1 Q99808 1/20 0.48
ADRB1 P08588 1/20 0.48
DNMT1 P26358 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14104915 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL6061826 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL17111255 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL17131379 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL13314307 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL6061829 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL17114382 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL2611620 1.00 ADK (0.56) ADKMTORRAB9ATK1HIF1A
SCHEMBL25468047 0.90 ADK (0.66) ADKMTORRAB9AHASPIN
SCHEMBL17762954 0.90 ADK (0.66) ADKMTORRAB9AHASPIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019227526-A1 FLUORESCENTLY LABELLED NUCLEOTIDE AND PREPARATION METHOD AND USE THEREOF 苏州百源基因技术有限公司 (CN) 2019-12-05 WO disclosed
WO-2014078652-A1 HEAVY ATOM LABELED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACID POLYMERS, AND USES THEREOF ZS GENETICS, INC. (US) 2014-05-22 WO disclosed