⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671778 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL1235535 | 0.77 | — | — | |
| SCHEMBL11116673 | 0.75 | — | — | |
| SCHEMBL2985000 | 0.75 | — | — | |
| SCHEMBL10974031 | 0.73 | ALDH1A1 (0.75) | — | |
| SCHEMBL10914858 | 0.73 | ALDH1A1 (0.56) | — | |
| SCHEMBL10970972 | 0.73 | ALDH1A1 (0.67) | — | |
| SCHEMBL10969480 | 0.73 | ALDH1A1 (0.67) | — | |
| SCHEMBL10975385 | 0.73 | ALDH1A1 (0.67) | — | |
| SCHEMBL11689701 | 0.72 | KMT2A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9026372-B2 | Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2015-05-05 | — | — | US | claimed |
| US-20110117050-A1 | Methods for Providing a System of Care for an Oxazaphosphorine Drug Regimen | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | US | claimed |
| US-20110097426-A1 | Methods for Safe and Effective Treatment Using Oxazaphosphorine Drugs | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | claimed |
| US-20110082115-A1 | Methods for Providing a System of Care for an Oxazaphosphorine Drug Regimen | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | US | claimed |
| WO-2009067690-A2 | METHODS FOR SAFE AND EFFECTIVE TREATMENT USING OXAZAPHOSPHORINE DRUGS | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | claimed |
| WO-2009067699-A2 | METHODS FOR PROVIDING A SYSTEM OF CARE FOR AN OXAZAPHOSPHORINE DRUG REGIMEN | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | claimed |
| US-20070060558-A1 | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents | PALUMED S.A. (FR) | 2007-03-15 | — | — | US | claimed |
| EP-1212055-A4 | NEUROTHERAPEUTIC COMPOSITION AND METHOD | REVAAX PHARMACEUTICALS LLC (US) | 2005-09-07 | — | — | EP | claimed |
| US-20030036541-A1 | Beta-lactamase inhibiting compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-02-20 | — | — | US | claimed |
| JP-2003506490-A | — | — | 2003-02-18 | — | — | JP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4267176-A | Amino or acylamino-substituted pyrimidinyl cephalosporanic acid derivatives and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4251657-A | Method for removing protective groups | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-17 | — | — | US | claimed |
| US-4200747-A | 7-2-Indolyl acetamido cephalosporin derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1980-04-29 | — | — | US | claimed |
| EP-0002586-A1 | Method for removing a halogenoacetyl protective group from a halogenoacetyl amino compound | Takeda Chemical Industries, Ltd. (JP) | 1979-06-27 | — | — | EP | claimed |
| US-4068071-A | DISULFIDING, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| US-4068072-A | CHLORINATION OR BROMINATION, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| US-4067979-A | Cephalosporins having an α-acyloxyacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | claimed |
| US-4048155-A | OXIDATION OF 7-BENZYLIDENEAMINO DERIVATIVE, REACTION WITH ALCOHOL | SANKYO COMPANY LIMITED (JA) | 1977-09-13 | — | — | US | claimed |
| US-4016155-A | Process for preparing cephalosporin derivatives | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | claimed |