SCHEMBL15740654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12436809	0.90	CYP19A1 (0.63)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL17142884	0.86	TSHR (0.69)	CYP19A1CYP2C9CYP2C19TSHRCYP1A2
	SCHEMBL17143201	0.86	TSHR (0.69)	CYP19A1CYP2C9CYP2C19TSHRCYP1A2
	SCHEMBL2151432	0.86	TSHR (0.69)	CYP19A1CYP2C9CYP2C19TSHRCYP1A2
	SCHEMBL25176182	0.85	CYP3A4 (0.61)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL9435138	0.85	CYP2D6 (0.91)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL9650521	0.85	CYP2D6 (0.91)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL15740967	0.85	CYP2D6 (0.91)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL30434302	0.85	CYP3A4 (0.61)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6
	SCHEMBL13527207	0.84	CYP2D6 (0.94)	CYP19A1CYP2C9CYP2C19CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.