SCHEMBL15744297

SCHEMBL15744297

CCCC1COC(c2ccc(-c3cc(F)c(C(F)(F)Br)c(F)c3)cc2)OC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
FASN P49327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13002438 0.89 FASN (0.36) CYP11B1CYP11B2FASN
SCHEMBL7851203 0.87
SCHEMBL7851204 0.87
SCHEMBL15744377 0.86
SCHEMBL15744298 0.86
SCHEMBL8456026 0.86 FASN (0.33) CYP11B1CYP11B2FASN
SCHEMBL15744524 0.86 ESR2 (0.31) CYP11B1CYP11B2
SCHEMBL1812007 0.85 RORC (0.30)
SCHEMBL18156644 0.85 FASN (0.44) FASN
SCHEMBL19844675 0.85 FASN (0.32) CYP11B1CYP11B2FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170349830-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2017-12-07 US disclosed
US-20170349830-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2017-12-07 US disclosed
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
US-9783735-B2 Liquid crystal display device and liquid crystal composition used therefor SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-10 US disclosed
EP-3222696-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2017-09-27 EP disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR DONGJIN SEMICHEM CO., LTD. (KR) 2016-10-20 US disclosed
EP-3081621-A2 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR Samsung Display Co., Ltd. (KR) 2016-10-19 EP disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
EP-2735599-B1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORP (JP) 2015-04-29 EP disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304783-A1 LIQUID CRYSTAL DISPLAY DEVICE AND LIQUID CRYSTAL COMPOSITION USED THEREFOR SLC39A11, CYP4F11, WEE1 CYP11B1 306/4885CYP11B2 491/4885FASN 2164/4885
US-20170349830-A1 LIQUID CRYSTAL COMPOUND CONTAINING DIFLUORMETHOXY BRIDGE, COMPOSITION AND APPLICATION THEREOF PLD1, CCND1, LPCAT1 CYP11B1 3874/4885CYP11B2 4223/4885FASN 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.