Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744468 | 0.90 | FASN (0.42) | FASNCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL15744605 | 0.90 | FASN (0.38) | FASNTHRBCYP2C9TP53MCHR1 | |
| SCHEMBL15744956 | 0.89 | FASN (0.44) | FASNTHRBCYP2C9TP53MCHR1 | |
| SCHEMBL15744345 | 0.86 | FASN (0.47) | FASNCYP2C9DGAT1 | |
| SCHEMBL15744382 | 0.85 | CYP2C9 (0.47) | FASNCYP2C9MCHR1MAPTALDH1A1 | |
| SCHEMBL15744318 | 0.80 | FASN (0.40) | FASNCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL15744989 | 0.80 | FASN (0.38) | FASNCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL12930554 | 0.79 | FASN (0.51) | FASNCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL16591211 | 0.79 | FASN (0.51) | FASNCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL14621251 | 0.78 | FASN (0.48) | FASNCYP2C9MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735599-A1 | Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device | JNC Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |