Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744407 | 0.90 | FASN (0.48) | FASNTHRBTP53MAPTMCHR1 | |
| SCHEMBL15745114 | 0.87 | THRB (0.35) | FASNTHRBTP53MAPTMCHR1 | |
| SCHEMBL15744480 | 0.84 | PRSS1 (0.33) | MAPTSMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL15744382 | 0.82 | CYP2C9 (0.47) | FASNMAPTMCHR1SMN1; SMN2KMT2A | |
| SCHEMBL15744468 | 0.80 | FASN (0.42) | FASNMAPTKMT2AGBA1ALDH1A1 | |
| SCHEMBL15744956 | 0.79 | FASN (0.44) | FASNTHRBTP53MAPTMCHR1 | |
| SCHEMBL10483942 | 0.78 | CYP11B1 (0.35) | SMN1; SMN2NPC1RAB9AKMT2AHIF1A | |
| SCHEMBL15744567 | 0.78 | KIF11 (0.30) | THRB | |
| SCHEMBL11249685 | 0.78 | KMT2A (0.41) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL14192462 | 0.77 | THRB (0.39) | THRBMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735599-A1 | Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device | JNC Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |